A decreasing supply of oil necessitates alternatives in powering vehicles to ensure mobility for future times. Hydrogen, natural gas and methanol are three of the most discussed replacements for common fuel. Even though some of these alternative concepts are still based on conventional internal combustion engines the fuel storage and supply systems contain a lot of differences. The question about the fire safety is one of the first asked in all cases the fuel system is affected. Various regulations ensure a high safety level but differences to conventional systems stay.