What are the guidelines on where to route a hydrogen stream from a PSV (Pressure Safety Valve) release or depressure system?

The routing will be dependent on the system design, size of release, and evaluation of the hazards.
Smaller systems are rarely vented to a flare due to complexity, availability and permitting considerations.
Facilities handling large amounts of hydrogen such as production plants will often have a flare system
since they have more capability for this additional onsite infrastructure.